Five Arsenal players and two each from Lazio, Atlético and Leipzig make up the first-leg XI.
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Note: While the FedEx Performance Zone is a form tracker taking into account domestic and European games, the Team of the Week is based purely on the UEFA Europa League matchday in question.
Péter Gulácsi (Leipzig)
One of only two goalkeepers to keep a clean sheet on the night, Gulácsi edged out Atlético's Jan Oblak as the highest-scoring keeper. He made three important saves and also scored highly thanks to his distribution.
Overall ranking 38 (+28)
Héctor Bellerín (Arsenal)
On a night when Mesut Özil was at his creative best, Bellerín added an assist from one of his many exciting raids down the right wing. His distribution was excellent with just four of his 53 passes going astray.
Overall ranking 64 (+39)
Diego Godín (Atlético)
The central defender was at his no-nonsense best on Thursday evening against Sporting. He made six clearances, three interceptions, won three aerial duels and two tackles to help maintain the clean sheet for his side.
Overall ranking 36 (+36)
Shkodran Mustafi (Arsenal)
While Arsenal did not manage a clean sheet, Mustafi played a vital role in restricting CSKA to one away goal. He contributed seven clearances, four interceptions and won four tackles in a strong defensive showing.
Overall ranking 17 (+4)
The full-back is renowned for his attacking efforts but his defensive play was exceptional against Sporting. His eight defensive interventions were important in helping Atlético register a clean sheet.
Overall ranking 18 (+8)
Emil Forsberg (Leipzig)
If Timo Werner grabbed the headlines, scoring the only goal of the game, it was Forsberg who was arguably the main man, supplying the assist in addition to his six crosses and four chances created.
Overall ranking 58 (+92)
Lazio's 31-year-old defensive midfielder is the only player to retain his place in the Team of the Week. Seven interceptions, five aerial duels won and five tackles won attested his defensive ability; he chipped in with an assist too.
Overall ranking 5 (+5)
Aaron Ramsey (Arsenal)
Ramsey got two goals as his late runs from midfield caused CSKA plenty of problems throughout. He hit the woodwork with another attempt and passed up several more chances – he could easily have had a hat-trick.
Overall ranking 10 (+25)
Senad Lulić (Lazio)
The midfielder was a constant thorn in Salzburg's side with his direct running style and crossing, yet he also underlined his finishing ability when his one attempt at goal secured Lazio a dream start to their tie.
Overall ranking 22 (+51)
Mesut Özil (Arsenal)
Arsenal's star playmaker produced an inspired first-half display as he helped himself to two more assists and earned the penalty as Arsenal marched into a 4-1 lead after only 35 minutes against CSKA.
Overall ranking 7 (+6)
Alexandre Lacazette (Arsenal)
The striker was playing just his second game since returning from seven weeks out injured, and he scored two more goals to follow his penalty against Stoke at the weekend and surge up the FedEx rankings.
Overall ranking 127 (+210)